7+ hour, 45+ min ago  (521+ words) A database containing the predicted structures of nearly every known protein on Earth has grown even larger and become more useful for understanding how the building blocks of life work together. For the first time, the AlphaFold protein-structure database will…...

7+ hour, 45+ min ago  (1058+ words) Russ, W. P. et al. An evolution-based model for designing chorismate mutase enzymes. Science 369, 440445 (2020). Shin, J.-E. et al. Protein design and variant prediction using autoregressive generative models. Nat. Commun. 12, 2403 (2021). Madani, A. et al. Large language models generate functional protein sequences across diverse families. Nat....

27+ min ago  (336+ words) Large language models (LLMs) include not only social stereotypes but also cognitive biases. As researchers work to identify, characterize and rectify these biases, we encourage the scientific community to recognize that, although often seen as errors, cognitive biases can also…...

57+ min ago  (1193+ words) Nature Methods (2026)Cite this article We thank C. Blish for helpful feedback during the project. J.Z. is supported by funding from the Chan-Zuckerberg Biohub. This work was supported by the National Science Foundation graduate research fellowship under grant no. DGE-2146755 (S.A.). Department of…...

7+ hour, 45+ min ago  (575+ words) Ramesh Srinivasan is the founder and director of the Digital Cultures Lab at the University of California, Los Angeles. Gilded Rage: Elon Musk and the Radicalization of Silicon Valley Jacob Silverman Bloomsbury Continuum (2025) In Gilded Rage, journalist Jacob Silverman describes…...

56+ min ago  (267+ words) The Education University of Hong Kong, Hong Kong, China. An artificial-intelligence bot can now pass 99.8% of attention-check questions in surveys (see Nature 650, 17; 2026). But this needn't be a threat: these checks were invented to catch careless human respondents. AI did not…...

1+ hour, 35+ min ago  (195+ words) Nature Methods (2026)Cite this article Tirosh, I. & Suva, M. L. Cancer Cell 42, 14971506 (2024). Zhou, J. et al. Adv. Sci. 11, 2407094 (2024). Zhou, J., Jiang, J., Han, Z., Wang, Z. & Gao, X. Brief. Bioinform. 26, bbaf505 (2025). Wolf, F. A., Angerer, P. & Theis, F. J. Genome Biol. 19, 15 (2018). Gayoso, A. et al. Nat. Biotechnol. 40, 163166 (2022). Wilk, A. J. et al. Nat. Med. 26, 10701076 (2020). Wang, W. et al. Nat....

1+ hour, 56+ min ago  (718+ words) Here, we utilize baseline and post-mobilization laboratory values to improve accuracy of single-timepoint prediction models. We demonstrate the performance of advanced deep learning models that can flexibly weigh routine laboratory data from both baseline and post-GCSF timepoints to accurately predict…...

2+ hour, 38+ min ago  (1737+ words) A connection between the relation of the generating-information function and other measures like extropy can be illustrated. Extropy, a unique measure of uncertainty that functions as a dual counterpart to entropy, was established by Lad et al.9 as follows A…...

2+ day, 7+ hour ago  (1687+ words) Therefore, this perspective paper will first establish a more formal framework for physical computing, then survey the different analog and algorithmic computers implemented in the soft robots, and discuss challenges and future directions in the end. On the other hand,…...